KJM9230 – Bioactive Molecules
Course description
Schedule, syllabus and examination date
Course content
This is an advanced course in organic chemistry emphasizing the chemistry of low molecular weight bioactive molecules, including natural products, their biological mechanisms of action, ADME properties, and general aspects of drug design. The course deals with the organic chemistry of important drug classes and bioactive natural substances. Synthesis/biosynthesis, mechanism of action, bioavailability, and stability for selected classes of drugs are discussed. The course is suitable for Ph.D. candidates in organic chemistry and related areas.
Learning outcome
After completing the course, you:
- can recognize the important classes of low molecular weight natural products and are?able to describe their biosynthetic pathways
- are familiar with general aspects of drug design
- understand and are?able to explain how drugs can exert their activity by interaction with receptors and enzyme
- are familiar with the use of peptides, proteins, and mimics as drugs
- understand and are?able to explain the important pathways for the metabolism of xenobiotics
- know the important classes of antibacterial incl antimycobacterial, antifungal, antiprotozoal, and antiviral drugs, and understand their mechanisms of action
- know the important classes of anticancer drugs and understand their mechanisms of action
Admission to the course
PhD candidates from the University of Oslo should apply for classes and register for examinations through?Studentweb.
If a course has limited intake capacity, priority will be given to PhD candidates who follow an individual education plan where this particular course is included. Some national researchers’ schools may have specific rules for ranking applicants for courses with limited intake capacity.
PhD candidates who have been admitted to another higher education institution must?apply for a position as a visiting student?within a given deadline.
Recommended previous knowledge
KJM3200 – Organic Chemistry II and partly KJM1140 – Biochemistry 1 for Chemists or BIOS1130 – Biokjemi 1
Overlapping courses
- 10 credits overlap w